DPCstruct | MC16261

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)254 ± 70 aa
Standard deviation of domain lengths70.28
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score91.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)19.50
Pfam Score92.86
Assigned Pfam label(s) PF19290- PF19289

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q3KZ91 33-297 AEADGQLQTEFWYDAQTHLEDLDPVEHVGHTAGHRAARMLGARPVATQVVPVIFEPQMAAGLLSGMLGALNGDMVTKKASFLRDKLG…
A0A6M1CKZ0 7-195 RTLSRLAPRKLATQKAPVIFAPEVATGLFGHLVGAISGTSVYRKSTFLLDSLGKQILPDWLTIRELPHVIGGLASTPFDSEGVRTED…
F7WYZ8 131-317 None
A0A7W8CVV0 279-578 None
A0A537ZMA0 319-625 None
K1YXE4 160-476 None
A0A1G6N1S5 134-330 None
A0A235III1 382-686 None
A0A662H787 2-180 None
A0A2X2TBB3 105-277 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.