DPCstruct | MC16249

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)82 ± 5 aa
Standard deviation of domain lengths4.78
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score83.06
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)69.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A447LEL8 75-156 RGIINVFKGLSWDYKSNSPCKFGKKIIVDGLVQYDRWGFHFRHGRRREQLADLDRMLNLLDGKPVPENRNDLSVRLDAHICK
K7ZYH9 3-84 RSVINEFESLSWNYRSNCLCYFGKKIIVESVVRYDRWGFHFSRGSRSNQLVDLERMLHLLDGKSVPDNRADIASRLDSRVSQ
A0A377LA23 59-137 None
A0A5U0W6C3 299-382 None
A0A3R0W8C4 18-101 None
A0A608K4I9 75-158 None
E0LU30 52-135 None
A0A167B3D7 86-167 None
A0A077NED4 6-87 None
A0A6D0EMX3 114-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.