DPCstruct | MC16229

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)183 ± 23 aa
Standard deviation of domain lengths22.71
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score88.46
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)19.83
Pfam Score71.43
Assigned Pfam label(s) PF09484- PF09709

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2BB13 14-189 DLLETYDTQKDTRCICPIAHTQIIANIGIMLDESSNILAAAKIRQSIFAPCTAKSECRSSNIAPHLIHDKVTYVSGINEKRHNAYME…
A0A359B306 1-189 MILLALKEYYDRKAADPESDIAPEGFEKKELQFLVVIDAQGRFINIEDTREKMGNKLVAKTFLLPRSVGRSGSRGYETTFLLWDHIG…
A0A517M0I0 2-203 None
U2CFN8 1-177 None
A0A369TA45 1-195 None
A0A221W3K7 2-172 None
A0A848CGQ7 16-154 None
A0A838QUV2 3-139 None
A0A833LUB8 2-193 None
A0A0Q5Q329 2-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.