DPCstruct | MC16227

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)299 ± 60 aa
Standard deviation of domain lengths59.70
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.19
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.84
Pfam Score77.22
Assigned Pfam label(s) PF11760- PF11761- PF01890

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A662J283 3-313 VLLWVPSADDESKAISSVLRSYGLEVKTVKGTISRARKYLYKSWNTLNFVIGIAPLPLCVRLISGLLKSKYEDPSVLCVTPDKNYVL…
A0A356UFK4 3-384 IAVITLTRQGTKLGEELSCKLPAVATADLPVTFNNETQDNYQFHLFVPVKFACPSKSVFLNGPQIYPRTQRFSFACPLRELVAYLFP…
A0A6I7PZN9 16-268 None
A0A412ZU32 5-319 None
W7SN62 107-470 None
A0A7W0ELE6 159-482 None
A0A7R9N701 4-289 None
A0A661PQM1 117-464 None
A0A7V3LX96 2-238 None
H0UMW2 3-324 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.