DPCstruct | MC16218

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)157 ± 11 aa
Standard deviation of domain lengths10.54
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score77.93
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)33.60
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3H628 6-161 EEIVMTPSKKGKATRIKIERKRRKELDPTQIAHEAGGQHKGLVVGKDIGEDKDDASPQLQLEFKCWLEDAKSGMHIPEGRLIKFWFV…
A0A0M9A2R9 3-160 EHIVMTPKCKTANSTTLIIERQALEPPKENGNENNVHVAGGDHKGIVINKQAAAVTNGEIHPAHLCLQFRVFLVSAQSGKHTQESRT…
A0A812BR42 2-166 None
A0A835G8U6 16-175 None
A0A443STB9 6-160 None
A0A1Y3EKZ1 4-167 None
A0A821EH85 13-164 None
A0A2P8YYH7 227-382 None
V4BP35 5-155 None
N1PB86 12-165 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.