DPCstruct | MC16154

Metacluster Properties and Pfam Annotations

Number of structural domains326
Mean domain length (aa)415 ± 92 aa
Standard deviation of domain lengths91.59
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.38
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.57
Pfam Score89.17
Assigned Pfam label(s) CL0109- PF05485- PF00621- CL0062- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A836M2T4 3-327 SGLILSWKFKYPVATAWSTAGLALIMATGSGYSLNEAIGAFLVGGLLTAILGFSGIFQKALSYIPQSLTSAMLAGVLLKFGISLFAS…
A0A2S2P4Y6 17-422 LGPTAIMAIMTRENIHDMGPEFAILLCFITGIVQLIMGFAQLGFLIDFISGPVSAGFTSAAAIVIATSQLKDLLGINIKANSFIGFW…
A0A7X9GAK3 2-238 None
A0A1Q9CC96 103-594 None
A0A2U1QM09 5-251 None
A0A3N5XKH4 231-658 None
A0A7R8X2U0 2-410 None
Q9SEV7 185-713 None
A0A6I9Z059 50-330 None
A0A248ZZE1 38-303 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.