DPCstruct | MC16078

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)127 ± 10 aa
Standard deviation of domain lengths10.35
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score74.13
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)33.48
Pfam Score88.10
Assigned Pfam label(s) PF05667- PF21674

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A402G1Z6 6-131 VESIREFTTELIVEAVVRCLRVINPSVGAGLSHILPPGMSARFRIGMSLAQAFQDLGYQGEIGYQTFLYSSEPEIRRLLLFLVEKLP…
A0A2R7WIS9 18-124 DINDEIDSLEGFTTDIVIDATVRCLEIIKPETNISRTLPQNMAARFHLGSAIAEACKNLGYSGEVGYQTFLYLNVGDVRRVFMFLIE…
B4DLA4 28-167 None
A0A5A8C378 22-156 None
A0A1X7T484 27-163 None
D3B059 380-512 None
A0A2I0VKN5 23-144 None
A0A5N6M017 26-135 None
A0A822BGG8 18-145 None
H9IVE1 1-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.