DPCstruct | MC16059

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)244 ± 20 aa
Standard deviation of domain lengths19.56
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score82.57
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0W8DAA9 195-448 AVRVFNLVRSRFDPNDLYLITMSFNIQEFEIRELKKKGPAMVGILTLVQDMQAETVDTFYMVALRYPYERVPTFELYERVGVTSDSY…
A0A2P4Y869 32-261 KTVARIYYLTRQKSNPKNVLLLSTMLSAQDYEVAQQFQRGAGMVLLVTAIDDMQTPELTHHIAVALNYPYAAEPEFAYSELQGIDGD…
A0A6G0W9I9 109-343 None
D0NQA1 36-288 None
A0A067CPJ0 111-345 None
A0A067CXB2 150-402 None
W4FYT9 12-298 None
K3X336 28-280 None
A0A485KUA8 91-289 None
A0A3R6VB48 157-415 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.