DPCstruct | MC16045

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)105 ± 11 aa
Standard deviation of domain lengths11.11
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score86.21
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)48.76
Pfam Score100.00
Assigned Pfam label(s) CL0530

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7LX09 66-176 IGTLLEQPSLYEEDVNSPEMLQRTLVTEEVRKQYISPPVPKQDVPLVYPEPGQPWIGRRIDYILYRETSISNLCRTELEEVTFISQL…
A0A401P241 17-115 YDEDTITPDNLQKVLESEEGRREYLVFSNCKNHPSSQKGRKIPLKSGGRRIDYALYSEDGLNPDWKVEMEEFSFVTQLAGLTDHLAV…
A0A437CIS4 702-805 None
A0A4W6D0U9 514-626 None
A0A3Q7RDF1 2-79 None
A0A6P8FAK1 684-794 None
A0A444TYA0 1-118 None
A0A2I0LI43 81-183 None
G3HKV1 300-410 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.