DPCstruct | MC16013

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)48 ± 2 aa
Standard deviation of domain lengths1.80
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score92.84
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.96
Mean intra-cluster local Distance Difference Test score0.96
Mean intra-cluster sequence similarity (%)53.31
Pfam Score100.00
Assigned Pfam label(s) PF02936

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2NRP4 68-115 QKRHVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWK
A0A811WK15 1-47 MAVLYSPLPETFDDEHQKAQLKRMLDLKVNPVDGLASKWDYENNRWK
H3C745 71-118 None
A0A6P7F1M9 95-144 None
A0A4U5UTQ0 161-208 None
A0A1W4W0K7 51-94 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.