DPCstruct | MC15981

Metacluster Properties and Pfam Annotations

Number of structural domains144
Mean domain length (aa)180 ± 27 aa
Standard deviation of domain lengths27.00
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score87.79
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.39
Pfam Score99.42
Assigned Pfam label(s) CL0047- CL0103

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B3KS02 389-585 LVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPGHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRSYRLQIHS…
A0A2C5YUF3 317-498 SHQHLFCLRVDPALDGHDNSLLVEESRPLEPSDPHGVGFAPRSRVVEREAGFDLDPASNRVFKLVNEGVRNPVSDTPVGFRLDPWPS…
S4RHK1 331-559 None
A0A2I0IE58 243-413 None
A0A2C9JXY0 534-713 None
A0A7J0GDK5 225-355 None
A0A378F3P1 5-156 None
A0A2V1DC62 442-653 None
A0A183TAP7 614-870 None
A0A1Q4E107 201-372 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.