DPCstruct | MC15978

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)437 ± 69 aa
Standard deviation of domain lengths68.86
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.56
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.32
Pfam Score87.78
Assigned Pfam label(s) PF12825- PF00787- PF12828

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C5YLR2 1-436 MNQDESRDESRDDSQDERQTKMALRPEQRRALFDILTHHQTYAEIQAFRRPETVTNYGFPISKSSPDDDDDNKKKLGSGSAPVLQML…
A0A010R0N5 9-507 LTAEQTKALFNILTHFETYHEIEDFKKPETISDYGYPFAQSSKPGETVTYAPESSAPLLQSLFTRFILKLPGVSSFVPEFWNVRVQG…
A0A2P4ZHL2 1-416 None
R1EYK6 1-407 None
I4YAX9 307-804 None
A0A5N5QTH1 491-963 None
M3HKY7 301-686 None
A0A0E9NNX4 59-556 None
A0A0D2Y2G0 2-324 None
A0A507F1V6 75-618 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.