DPCstruct | MC15946

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)173 ± 10 aa
Standard deviation of domain lengths9.71
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score76.97
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)47.19
Pfam Score100.00
Assigned Pfam label(s) CL0465

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452EVK9 8-177 RSECVAALLMAGADLTAVDPVRGKTALEWAFLTDSFDTVQRIRQLLRRPQVEQLSRHYQPEWPALPGLVAQAQAAPSLLERLQATLT…
A0A4W5LX71 4-169 MPLLICVFPLLGADVEARDYSRKMTSREWALFTCRYETAYLMMRLMAQPCAQQFCDSYKLEWPMLQELVAQRQESKSCWQKVADKVC…
A0A665V1N2 2-186 None
A0A7M4E157 8-183 None
A0A670YNI0 12-174 None
A0A673AZX9 1-156 None
A0A3B4GUI9 9-183 None
A0A452VA69 1-183 None
A0A3B5KBN0 10-181 None
A0A671M033 28-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.