DPCstruct | MC15935

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)106 ± 8 aa
Standard deviation of domain lengths8.20
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.67
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)41.80
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3R342 6-112 LNTTDVTVIDQLRAILRNAIYPVRINNLIQITGVNMSTVCYPNGTGFQCRCEDQYRWSCDQCVSYGNCDDITSDTCGCINAIPPDGQ…
A0A4W5LEY1 1-101 MTDISATLIDVLRASVNGLIYPVLISNVLNVTDVNFTTACYPNSTCRCEDQYGWSCDQCLAFESCDNITDDSCGCIKAIPPYGLFCQ…
A0A498M757 9-106 None
A0A6P8SMZ8 201-319 None
H3C4K8 129-242 None
A0A4Z2J451 123-226 None
A0A498NYA5 432-527 None
A0A6P8SLN1 164-279 None
A0A2D0QIP6 16-112 None
A0A6P8V0K6 60-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.