DPCstruct | MC15912

Metacluster Properties and Pfam Annotations

Number of structural domains310
Mean domain length (aa)147 ± 36 aa
Standard deviation of domain lengths36.10
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score79.49
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)33.84
Pfam Score97.15
Assigned Pfam label(s) PF02515- CL0063- CL0020- CL0442- PF16101

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A098E8M6 1-184 MYAFIGIGQGGCGLLDSAFYDKDLFKVAKPIAINSTAKDLKNLKHIKQEYWLGMSKDKGFIDGTTKNLESYLVGGYGQDRTKSKDDA…
A0A813HXB2 1-150 MREALCIHLGQGGVQIGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRCVMVDLEPTVVDEVRTGTYRQLF…
A0A842X6Z5 21-196 None
A0A1R3KMF2 3-153 None
A0A2V1D074 150-300 None
A0A7R9A3B1 2-110 None
A0A7R8X2X5 1-163 None
A0A6J5VNR4 16-127 None
A0A821CCJ5 2-145 None
A0A2D0PJZ2 2-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.