DPCstruct | MC15822

Metacluster Properties and Pfam Annotations

Number of structural domains344
Mean domain length (aa)305 ± 89 aa
Standard deviation of domain lengths88.53
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score80.12
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)18.52
Pfam Score82.24
Assigned Pfam label(s) CL0063- CL0257- CL0129- CL0442- CL0588

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S8L876 32-319 LFFNSSALDIKPLKNAEIDKNVYLYPGTDGSGRDRRKSREMIKDNANAIGTLLKKYPQTEVMVIFASFAGGTGSGAIKTFIQIAASA…
A0A1D2RC48 45-376 VSEEGKLVAGFEGMVVGGFGGDPDKVEKVVSEHYNNFKNLLSKRIRKGSHADIRAKRERIASFAFLSVGLGGGTGSCIAPYVAQAIK…
A0A7R8X2X5 45-451 None
A0A178EKC6 445-833 None
A0A843M9L8 34-408 None
V5A299 2-199 None
A0A1S8W3N3 2-238 None
A0A3S7X6J0 4-200 None
A0A0E0I012 272-664 None
A0A6A0JSF1 65-436 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.