DPCstruct | MC15757

Metacluster Properties and Pfam Annotations

Number of structural domains1535
Mean domain length (aa)310 ± 79 aa
Standard deviation of domain lengths79.35
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score87.78
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.38
Mean intra-cluster sequence similarity (%)13.56
Pfam Score99.12
Assigned Pfam label(s) CL0020- CL0056- CL0077- PF11658- PF11893

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6C2U1K6 27-474 None
A0A194VQ71 2-315 None
A0A7C2KW64 10-407 None
A0A2S8PEE1 454-810 None
A0A7R7VJC2 17-249 None
A0A4Q4XBL0 424-801 None
A0A0E3SRU8 9-263 None
A0A6L7TSE4 3-269 None
A0A818EQY8 366-678 None
A0A7Y4SV02 158-457 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.