DPCstruct | MC15757

Metacluster Properties and Pfam Annotations

Number of structural domains1535
Mean domain length (aa)310 ± 79 aa
Standard deviation of domain lengths79.35
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score87.78
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.38
Mean intra-cluster sequence similarity (%)13.56
Pfam Score99.12
Assigned Pfam label(s) CL0020- CL0056- CL0077- PF11658- PF11893

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Y9NUF1 5-363 DLGVYGEPSRETPNLDRMAAEGMLFPNFYTANPLCSPSRAALLTGRLPIRSGFYTTNGHARNAYTPQEIVGGIPDSELLLPELLKEA…
A0A800AKF6 165-498 RKPEKPNVLLISIDTLRADHLSCYGYHRRTSPNIDKLAQEGILFKNTFSQCSWTIPSHGSIFTSKLPHRHGGTIDTAPGGTWHPLPF…
A0A1W1XDV9 13-306 None
A0A2D5WIA6 685-1031 None
A0A2P9I6G2 6-330 None
R5LKQ5 27-230 None
A0A2E1H454 155-407 None
A0A7C8GIY7 3-203 None
A0A5B7DD06 11-443 None
A0A350IXB5 267-583 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.