DPCstruct | MC1566

Metacluster Properties and Pfam Annotations

Number of structural domains223
Mean domain length (aa)155 ± 30 aa
Standard deviation of domain lengths29.88
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.93
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)25.93
Pfam Score95.08
Assigned Pfam label(s) CL0270- PF00330- CL0063- CL0364- CL0381

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V6UUY5 32-187 ISPAGAAVLVFRSNVPAIAEHCFKYVDAEFVARAKAAGRGIIVGGEIYGQGSSREAAAVGPMHLGIRAVIVKSFARIHRANLINWGI…
A0A821Z689 79-228 QDLTDMPILMKIKGKCTTDHISPAGVWLKYRGHLDNISNNMLIGAINEENGEANNIQNTMTNQQGKVPDTARYYQSKNIPWVVIGDQ…
A0A158IL83 30-179 None
A0A7J0G2B0 166-316 None
A0A835CTA6 234-368 None
A0A484YK36 30-180 None
A0A1Y1U7A2 456-584 None
A0A7C7IUC1 11-157 None
A0A2P2H6V5 662-810 None
A0A4Q4W4Z4 26-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.