DPCstruct | MC15647

Metacluster Properties and Pfam Annotations

Number of structural domains147
Mean domain length (aa)169 ± 32 aa
Standard deviation of domain lengths31.80
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.41
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)25.17
Pfam Score98.11
Assigned Pfam label(s) CL0039- PF10148- PF01871

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A843HQE4 6-132 IGYPEPVYPLIDAVIDSASSAAMRDPRFPSVDESELDSLEYEITVLTKPQIIEVEKPIDYLDNIIIGEDGLIVERGFYRGLLLPQVA…
J9EK21 9-169 YDQAFDDIGDHPLFVTYNLNDKLRGCIGTFKADKLGKQLQSYSLVAALYDKRFNPLSKKELQQVQCEISLLTEFEKINDVHEWEVGK…
U6LYG9 184-379 None
A0A7C2XTQ6 25-196 None
A0A7C5LK60 351-529 None
A0A7J3ZAU0 5-155 None
A0A3C0PH34 335-519 None
A0A482WX94 24-251 None
A0A6P8S8F4 72-252 None
A0A7R8GZ51 3-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.