DPCstruct | MC15592

Metacluster Properties and Pfam Annotations

Number of structural domains499
Mean domain length (aa)219 ± 46 aa
Standard deviation of domain lengths45.65
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.90
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.26
Pfam Score98.76
Assigned Pfam label(s) CL0052- CL0472- CL0612- CL0067- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4X8G6 351-623 None
A0A453FCW6 35-359 None
A0A4R0RMT2 552-802 None
A0A2U1J3D2 11-252 None
A0A402FH55 1-188 None
A0A1M4WFJ5 1-182 None
A0A3M1LHC4 2-217 None
A0A364MYR6 554-777 None
A0A2D8XAC3 489-720 None
A0A180H0I4 142-475 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.