DPCstruct | MC15592

Metacluster Properties and Pfam Annotations

Number of structural domains499
Mean domain length (aa)219 ± 46 aa
Standard deviation of domain lengths45.65
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.90
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.26
Pfam Score98.76
Assigned Pfam label(s) CL0052- CL0472- CL0612- CL0067- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M5EDH3 1-179 None
A0A542YMT0 45-217 None
U1HSA2 110-346 None
A0A6C0ID07 5-185 None
A0A553RB59 1-282 None
A0A814WRY6 267-468 None
A0A1Q6ETF7 1-148 None
D8LUR9 315-559 None
A0A1R1XEX9 2-213 None
A0A656PMQ2 1-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.