DPCstruct | MC15558

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)84 ± 10 aa
Standard deviation of domain lengths9.79
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score68.46
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)49.32
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6N7WXH2 40-124 LELPMDDMDLTSAESKATYKQIQNYVLEKYGFKVSNLYIAQVKEKYGIKERENYNKRKNNDSKQPICPIEKEEAIKDAFRYFQMI
A0A7U9SI98 84-166 LDLDEMDLTAAEKKATYEEIKAYVKEYTGLKVSNLYIAQVKQKCGIIERENYNKPKSEGTRQPQCPLEKEAAIKAALEHFGMI
A0A415P8S4 396-480 None
R5HRE3 2-75 None
A0A133ZYK7 118-202 None
A0A1C6DYS3 1-114 None
A0A3C0P282 273-352 None
A0A8A8TPF4 16-95 None
A0A095YX97 292-379 None
A0A416LG19 3-79 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.