DPCstruct | MC15493

Metacluster Properties and Pfam Annotations

Number of structural domains258
Mean domain length (aa)87 ± 12 aa
Standard deviation of domain lengths11.53
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.08
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)25.65
Pfam Score94.37
Assigned Pfam label(s) PF12140- PF16616- CL0003- CL0004- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W5NHE2 324-401 None
A0A182HCG4 226-316 None
A0A7S2ICN0 56-131 None
Q9VB52 1297-1381 None
A0A819TFA1 533-635 None
A0A397VTG5 8-79 None
A0A7I4YQW7 734-820 None
A0A3S5AC04 787-876 None
A0A834R5B0 501-600 None
A0A6P6JAP1 289-362 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.