DPCstruct | MC15493

Metacluster Properties and Pfam Annotations

Number of structural domains258
Mean domain length (aa)87 ± 12 aa
Standard deviation of domain lengths11.53
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.08
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)25.65
Pfam Score94.37
Assigned Pfam label(s) PF12140- PF16616- CL0003- CL0004- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A397WB42 1-86 MSTFNFTTNILTFETIQGWEVETVEAFLKFKQKDFSLSDAEIQKFVDGSVNGPMLLEVNRDDLISLLGLRLGPALNVSAFAENLKN
A0A3Q2YTK7 2-72 PFPLEWSVTDVVRFIRTTDCAPLARIFMDQEIDGQALLLLNLPTVQECMDLKLGPAIKLCHHIERVKLAQV
A0A5J4YY24 248-318 None
A0A7N8XPN6 430-516 None
A0A397SR88 7-94 None
A0A397SPL3 1-104 None
A0A397SMQ7 6-89 None
A0A397SLQ1 2-96 None
A0A397SAU0 99-178 None
A0A819X1H6 723-826 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.