DPCstruct | MC1546

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)583 ± 121 aa
Standard deviation of domain lengths121.06
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.23
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)16.34
Pfam Score97.62
Assigned Pfam label(s) PF04112- CL0662

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J1U964 25-594 GNTSWIDITQDFEDCCKELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKVKDLSLPELIGIMDT…
A0A2P7YTQ4 226-887 YVDVTDRFFRSVEGMKPGNVVASQYFDMLEGSRAIEIGNLRLDTGLIKLKQEEIMFDAAAPQDVDNVLGSMNHITMLLMLWFLGLSL…
A0A0F7SL68 5-623 None
A0A364MVI1 336-1033 None
A0A1B7P584 62-457 None
A0A194Q2B3 268-938 None
A0A5K4EFD3 1-642 None
A0A453PYE7 5-340 None
A0A6V7U7M1 12-451 None
A0A1R0H185 1-692 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.