DPCstruct | MC15448

Metacluster Properties and Pfam Annotations

Number of structural domains4317
Mean domain length (aa)133 ± 26 aa
Standard deviation of domain lengths26.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.64
Pfam Score91.17
Assigned Pfam label(s) CL0020- PF18701- CL0177- CL0153- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182ESI6 288-410 None
A0A0Q4JPM8 99-218 None
A0A7S1MV15 23-194 None
A0A5N6N8M2 126-231 None
A0A5N6NGV7 224-344 None
A0A5N6NIJ5 191-328 None
A0A5N6NNV7 336-483 None
A0A1S8XBB2 225-356 None
A0A0F7TE92 4-162 None
A0A2P4VGF5 6-119 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.