DPCstruct | MC15448

Metacluster Properties and Pfam Annotations

Number of structural domains4317
Mean domain length (aa)133 ± 26 aa
Standard deviation of domain lengths26.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.64
Pfam Score91.17
Assigned Pfam label(s) CL0020- PF18701- CL0177- CL0153- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445ATR4 25-174 None
A0A5C3K9K6 5-130 None
A0A512BCM0 162-286 None
A0A7Y4SRJ3 192-335 None
A0A699S6B8 13-119 None
A0A8B6DEE1 166-306 None
A0A8B6DEI7 369-540 None
A0A8B6DJA6 36-157 None
A0A8B6DJH7 9-123 None
A0A8B6DLC5 2-106 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.