DPCstruct | MC15448

Metacluster Properties and Pfam Annotations

Number of structural domains4317
Mean domain length (aa)133 ± 26 aa
Standard deviation of domain lengths26.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.64
Pfam Score91.17
Assigned Pfam label(s) CL0020- PF18701- CL0177- CL0153- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6L2JUB3 124-274 None
E2BG33 607-724 None
A0A4Y9ZT08 105-269 None
A0A7U0XSR2 3-119 None
A0A238FNQ1 1156-1263 None
A0A821JKY8 234-358 None
A0A2T7DNL2 26-135 None
A0A6H5HQP7 412-492 None
A0A7J0EWP0 168-318 None
A0A7J0EXP8 427-543 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.