DPCstruct | MC15448

Metacluster Properties and Pfam Annotations

Number of structural domains4317
Mean domain length (aa)133 ± 26 aa
Standard deviation of domain lengths26.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.64
Pfam Score91.17
Assigned Pfam label(s) CL0020- PF18701- CL0177- CL0153- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3BC74 174-290 None
E9G0L7 189-335 None
E9G7W1 237-390 None
A0A7E4VT18 155-291 None
A0A7E4VU90 56-201 None
A0A7E4VWV3 38-177 None
A0A1U7WH14 109-227 None
A0A2B4RZP8 145-288 None
A0A4Y2U3G5 3-109 None
A0A317AND9 4-131 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.