DPCstruct | MC15448

Metacluster Properties and Pfam Annotations

Number of structural domains4317
Mean domain length (aa)133 ± 26 aa
Standard deviation of domain lengths26.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.64
Pfam Score91.17
Assigned Pfam label(s) CL0020- PF18701- CL0177- CL0153- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812TCF6 1-124 MKSVAGTKWVNQHIQRLKSLGRWMKAVPERESFRFGDGHEVWSEFSFIFEATLLGVRVVLRLSVVPGDCPPLLSKPACTQLGIVIDT…
A0A6A4AUT0 14-133 DHEQEGSREVTLVHGAVNDLRVQILLDTGTSGSMASLNLARRLKLKLQVLPEPIKVSGLGGVPSYITASAKVKITLEVRVVYITNVW…
A0A1J9RH95 62-217 None
A0A3S0ZLF6 83-237 None
A0A2D0QJ66 238-378 None
A0A803J5T0 91-205 None
A0A6D2I6C7 63-200 None
A0A6D2I4J7 157-252 None
A0A6D2HVU5 184-287 None
A0A6D2HZP3 37-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.