DPCstruct | MC15389

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)92 ± 12 aa
Standard deviation of domain lengths12.32
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score79.44
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)46.65
Pfam Score92.40
Assigned Pfam label(s) CL0023- CL0357- CL0181

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K1PZU3 366-451 SAIKYGELIILGYNGHLPSGDKGRKKSKFILGKKPSGNGVKPFRKHVVKNAQAAKALQDPQSHSVTYTLSRHQAVVVEYKQDEDTD
A0A368GKS5 42-131 KYGELILLGYNGSQDSRATVPLKRHRTKMALMRRKNGNGIKKGSVTQVNIAAKDAPAVLDKNRHVVSYSYGKNQTVLVEYVADPFKD…
A0A183H5E5 141-236 None
A0A4Z2FTS8 6-101 None
A0A4C1VC99 55-145 None
A0A7J7VJL7 17-124 None
A0A7R9P9Z9 22-124 None
A0A060ZAT7 22-134 None
A0A654H2D3 5-91 None
A0A0K2UQJ0 22-107 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.