DPCstruct | MC15372

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)145 ± 14 aa
Standard deviation of domain lengths13.78
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score74.10
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)23.83
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A132B8T5 1-139 MEKSKEASVEKCRDGKEGQKSASANAKSYKGLLKSLARMRQQPNRHEELASKTSQWTWTNKQCREWITAVSVWYLGYDEVDGEKAAA…
A0A2J6QZL4 18-160 QSPPPAYEDGSTAGTSLANSAPSISPSSSTTPKPRKSLATFLRPFAKRIRAADTPQWAWSNVQCREWLAAVLVEYCNRDPVVARELA…
A0A2V1BHL9 34-191 None
A0A132B8D5 61-208 None
A0A194X9J2 2-145 None
A0A194X1J6 1-135 None
S3DV27 2-111 None
A0A7D8YNB7 26-184 None
A0A4Z1KYM6 19-172 None
A0A2J6RH68 89-238 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.