DPCstruct | MC15336

Metacluster Properties and Pfam Annotations

Number of structural domains160
Mean domain length (aa)176 ± 43 aa
Standard deviation of domain lengths43.43
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.39
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)15.59
Pfam Score98.72
Assigned Pfam label(s) CL0190- CL0350

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A538ITU2 3-123 LHGIQLGRPIDLLLDRDARRAVGLDVFCGDEVHRFLPLPTAAVGRAEIRILSPLVLLEQRELDFYRSRTLALSRLRGAPVERNGRRL…
A0A7K3ZJS7 2-170 ATRTLDQFYGMEVATMDAFLMGSVFDLRYNTKDWKVAGLMVRGSKRVMSEAPSSASGSAILLKPGRFVMNDICIVPDRMDRAIREIT…
A0A7X1PBB3 21-276 None
A0A3D4ZWR2 1-167 None
A0A168NQC1 6-142 None
A0A838L2X1 57-203 None
A0A4Q6G284 32-215 None
A0A316KGD2 5-213 None
A0A3R8Q2L7 2-195 None
K8F337 235-395 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.