DPCstruct | MC15327

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)130 ± 23 aa
Standard deviation of domain lengths22.80
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score75.22
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)37.42
Pfam Score100.00
Assigned Pfam label(s) CL0375

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q2XD46 125-228 GLWWTYLISLFAKTGIEIAFLYILHRIYNSFYLPRLVKCEVSPCPNIVDCYIGHPTEKKVFTYFMVGASALCIVLNICEIFYLIYKR…
G1U794 1-182 MLGLGEDAEEEPGAPEGPAEDAEEERAEEAATKGAGGGGEAAGTPGPATQHDGRRRIQREGLMRVYVVQLVVRAAFEVAFLVGQYLL…
H2Y5A5 92-185 None
A0A6J0I1S2 204-335 None
A0A1L8HJ47 214-309 None
M7BS41 73-231 None
A0A5C6NIL1 408-529 None
A0A668A3Q7 25-167 None
Q6DEG1 112-212 None
A0A654ICJ2 18-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.