DPCstruct | MC15307

Metacluster Properties and Pfam Annotations

Number of structural domains120
Mean domain length (aa)213 ± 42 aa
Standard deviation of domain lengths41.89
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.93
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.04
Pfam Score61.31
Assigned Pfam label(s) CL0163- PF04152- PF12320

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H7C818 23-229 LTGHLHVAGGIESEGAERRILVGGQHAVPHDVFPAEASYVALGHLHKAQAIGRDTIRYSGSLIPLSATEMPYAHGVTLVSLDGTTVL…
R5J3H3 43-228 IQILMAHGGDAAHLPINFNSLELSPFSYIALGHIHKPQVISEDKIAYCGSPEPLDLTETGVHGYFTGEIHPETHKLTHLEFVPAATL…
A0A7M7NCG3 199-443 None
B0EB30 185-393 None
A0A2S4MDB3 93-313 None
A0A7C5MJS9 47-294 None
A0A6L5G3L7 130-358 None
A0A3A0CPJ2 156-336 None
A0A2P4ZPD5 161-364 None
A0A2X2CKP8 34-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.