DPCstruct | MC15177

Metacluster Properties and Pfam Annotations

Number of structural domains279
Mean domain length (aa)187 ± 36 aa
Standard deviation of domain lengths36.35
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score78.89
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)14.06
Pfam Score29.13
Assigned Pfam label(s) PF11041- PF10076- PF09684- PF06996- PF04865

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5Q0L6B7 14-180 IGAMLPAVFADDDLALRFVAGLDEVVAPILLALDCLHSYFDPALAPADFARWLGTWVGAELDGSEPDDRLRAAVAAAAYLHRVRGTR…
A0A7Y5GUQ7 8-196 RLLLPRWLKNEDGELWRLTEALGQVADDARSAVDRVRRLWVTETSSSAGLDAIGAGRACERWDDESDAEYRQRLVALFGVRMRAATP…
A0A348HEA2 3-193 None
A0A354TCE1 8-210 None
A0A843GEX3 4-187 None
A0A843FL67 453-689 None
A0A6J4LB46 59-223 None
A0A0Q4IS19 70-249 None
A0A3B0BNM3 836-1010 None
A0A7U7FD77 2-204 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.