DPCstruct | MC15138

Metacluster Properties and Pfam Annotations

Number of structural domains440
Mean domain length (aa)192 ± 33 aa
Standard deviation of domain lengths33.08
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.72
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)11.92
Pfam Score66.62
Assigned Pfam label(s) CL0648- PF14613- CL0027- PF19343- PF14356

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A226EFI4 19-215 SKRDTKIKQPVLQLNGTTLTDKVMDSVRAEVIKQGWDDINPPDVVLKDPFGFSNYSLAIRNQSIKGMANAYRVGDVIVNVTILNTKF…
A0A2A4JLY9 29-226 CKWDDSKCIKGSAQSAIPILAAGIPELGVEKLDPFYMKSLDASSNGLNLQLWDIKGTGLSGCVAKKMQRDINKSKLIVKLQCSVDFV…
A0A3Q0JFJ1 299-499 None
A0A182TTJ6 3-161 None
A0A182U5A7 1-158 None
A0A7R9NYC6 5-146 None
A0A834XI77 35-223 None
A0A370PJ13 110-331 None
A0A3Q0JFG3 2-153 None
A0A834Y7P7 40-198 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.