DPCstruct | MC15018

Metacluster Properties and Pfam Annotations

Number of structural domains161
Mean domain length (aa)74 ± 10 aa
Standard deviation of domain lengths9.93
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score89.57
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)41.43
Pfam Score99.56
Assigned Pfam label(s) CL0027- PF00777

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W6EG72 126-194 CRSCAVVGNSGNLRRSGHGSLIDSHTFVIRMNKAVTRGFEKDVGNRTTHHFLYPESAVDVAKGVSLVLL
A0A2U9C4L9 97-163 MHCRTCALVTSSGQLTGSRRGEEIDRSECVIRMNDAPSEGCQRDVGQRTSLRVIAHSSLQRVLRSRQ
A0A5B8MZT6 310-398 None
A0A498NRN9 57-127 None
A0A498NS27 3-67 None
A0A3L8SDT9 64-136 None
A0A498NSX6 73-138 None
A0A2K1JE63 76-140 None
A0A7M4FIN9 59-131 None
V9L8L8 143-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.