DPCstruct | MC15017

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)702 ± 81 aa
Standard deviation of domain lengths80.97
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score82.29
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)40.73
Pfam Score88.79
Assigned Pfam label(s) CL0689- PF11598- CL0053- CL0004- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R7VCA2 8-583 GKSYTGSKNQTCADVDECAFNNGGCDVNSFCYNTIGSFYCGFCHKGYLGDAHYGCYDDNFCRSGADKCHAQARCSYAGPGEYRCQCQ…
A0A3R7QCY9 152-838 RFFSCESAGSKPEGYRCQDNMIFDEALGLCRNKESTLSCTEAGLFAIPKSCSDYFSCIPLRHGWVQRFYMCTNNRYFSQKSEACKDP…
A0A7M5U9K6 237-1024 None
A0A6J8B379 1-711 None
A0A5N4AN02 386-1195 None
A0A556VTY1 76-713 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.