DPCstruct | MC14998

Metacluster Properties and Pfam Annotations

Number of structural domains188
Mean domain length (aa)191 ± 38 aa
Standard deviation of domain lengths38.31
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)32.17
Pfam Score92.09
Assigned Pfam label(s) PF00926- PF00925- PF12471

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5A8DNM1 65-272 None
A0A167CEM0 486-739 None
A0A4R5XR15 19-228 None
A0A2R6Y054 336-521 None
A0A2W4TR04 64-262 None
M8CSH8 467-673 None
A0A2B9SUS3 2-147 None
A0A4Q0Z3L2 110-293 None
A0A6A6K116 96-293 None
A0A5S9ISI1 742-928 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.