DPCstruct | MC14998

Metacluster Properties and Pfam Annotations

Number of structural domains188
Mean domain length (aa)191 ± 38 aa
Standard deviation of domain lengths38.31
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)32.17
Pfam Score92.09
Assigned Pfam label(s) PF00926- PF00925- PF12471

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A838VTC4 1-155 SDVFGSDICTCRPYLAHGIEVCVQTAQEGGVGIIIYCRKEGRALGEVTKFLVYNARKRQVGGDRADAYFSRTECVAGVQDMRFQELM…
A0A7D6Z9L1 30-219 RTRHSLTRLRHKIDMRCVPLPDNSGHVVIFGDAEFRRHPFVRIHSRCLYGDVLGSDDCDCGPELQRSIATMRASGAGILVYLEQEGR…
K9PWL8 206-403 None
G8BC40 157-412 None
A0A838LA99 437-624 None
A0A7X7QFL5 52-263 None
A0A511D354 8-194 None
A0A1R0H4G5 44-280 None
A0A6N7G1R2 14-213 None
A0A511D5Z4 215-417 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.