DPCstruct | MC14994

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)126 ± 20 aa
Standard deviation of domain lengths20.06
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.88
Mean fraction of residues predicted as intrinsically disordered0.53
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)30.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A848D066 6-114 RASIETFKSNPKVFSGKSAEEIAKMLEDAGYKVTVQASKRSRSGAKIIKIQNTGREKNITQVQVSPGGGRHGDSPYVKISTSDQGII…
A0A7X1PPH8 10-137 SGSSKLSKVTDGSSGSGGQAAKANINIAKDFISKPQSIWGRSADEIANDFRAAGYEINVRQSTRGSGQALIVEVKGHPQISQIQVHP…
A0A836MNR5 70-188 None
A0A4Y1KH88 70-174 None
A0A837KNV0 57-210 None
A0A829R4L4 197-341 None
A0A127PD59 205-338 None
A0A2T5RX88 178-311 None
A0A1Y3NWJ0 6-102 None
A0A2V3QRZ8 392-527 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.