DPCstruct | MC14988

Metacluster Properties and Pfam Annotations

Number of structural domains74
Mean domain length (aa)418 ± 103 aa
Standard deviation of domain lengths102.98
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score76.04
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)27.66
Pfam Score52.40
Assigned Pfam label(s) PF14288- CL0111

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I1C363 1-366 MLQLKDLEHKWRVRMEQMPDTEKLQQLALWLMLWGEASVIRFCPELLCFIFKLADDMLRENPSIDSVQEGDYLDNVITPLYIFIRNQ…
A0A7J9NBD4 78-437 FFCFQHENFKNQREHLVLHLANSQMRLSPLPENIDTLDAGVLRTFCQKLLKNYTNWCFYLGKKSNVWISKSGHSNSDHSRELLYVGL…
A0A835RI76 1-326 None
A0A835R3F1 301-670 None
A0A287HXB3 98-518 None
A0A388KY40 154-605 None
A0A2P2MBJ8 261-650 None
A0A438DAG5 42-352 None
A0A2N9INZ6 1-319 None
A0A287Y0V3 2-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.