DPCstruct | MC14979

Metacluster Properties and Pfam Annotations

Number of structural domains131
Mean domain length (aa)174 ± 22 aa
Standard deviation of domain lengths22.34
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.91
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)18.44
Pfam Score53.83
Assigned Pfam label(s) CL0123- CL0010- CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H1DCC6 3-160 IELIDGKDYFKIKYADEDKLFVPLESIHKIEKYVHVPGVVPEIYHLGTRGFQRKREKLQEEILEFAKEIVEIQARRNSTQGFRYSPD…
A0A377TQ77 316-490 LHIGQPVVHLEHGVGRYAGMTTLEAGGITGEYLMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWTRARQKAAEKVRD…
D8LDP5 2-168 None
A0A7C5J6A2 2-156 None
A0A837PYP3 312-420 None
A0A524RR41 1-161 None
A0A379UN59 2-155 None
A0A3A1VQN2 209-387 None
A0A7V2HXU7 240-408 None
A0A7C7EBQ9 1-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.