DPCstruct | MC14978

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)90 ± 11 aa
Standard deviation of domain lengths10.69
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score77.43
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)65.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377TPB0 1-89 MIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFLRPGRVGEVSVIGIVLLVASIWFGGVIAHDPYWGPALTFKTPPSP…
A0A6G3VE49 1-102 TAAIVAVFVIMIILIAVLALVVVNALAESPWGVFSIAMTIPIALFMGVYLRYLRPGRVSEVSLIGVVLLLGAIVAGRYVGESSWGND…
A0A2X2VGT7 28-128 None
X8APK4 105-189 None
A0A6D0EPB4 21-102 None
A0A2X3DRG2 2-73 None
A0A377M7B8 316-416 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.