DPCstruct | MC14974

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)185 ± 18 aa
Standard deviation of domain lengths18.00
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score85.97
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.72
Pfam Score0.00
Assigned Pfam label(s) CL0264- CL0287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377Z1N1 49-227 RAIVGFGHSFIANPRFLRTLSDLTGLPTYNFGRSGGLSRTVALRAGAYTVSYEPVGGLIPESGPVVLSPADPGVLQIVGNAALSETV…
A0A377TIG7 216-393 PKIVGWGHSFMENGRFLSRLAQLTGLYTYNFGKSGLTSEGVASRQGAARTFYTPAGGVIPASGAVTLSPAKPGPNRIFGNAAATSIA…
A0A2W1PBE8 50-218 None
A0A172YG33 117-331 None
A0A6I4TUN8 453-647 None
A0A545B7W3 555-753 None
A0A0Q4DNT1 22-201 None
A0A1V0GVT5 265-456 None
A0A260WFW1 166-340 None
A0A427CT03 288-453 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.