DPCstruct | MC14949

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)94 ± 10 aa
Standard deviation of domain lengths9.88
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score81.73
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)55.31
Pfam Score100.00
Assigned Pfam label(s) CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Z4PRN2 132-206 LVAAAQKTNRLELAHKAIEIAETRLMQDKWPEYYDGKNGRLIGKEARIYQTWTIGGYLVAKDLISNPRHLELLCF
A0A6J0KLW6 67-157 LWQLTATCIKTGRPQIARRAVDLIESRLHRDCWPEYYDGKLGRYVGKQARKYQTWSIAGYLVAKMLLEDPSHIGMISLEEDKLMKPV…
A0A164Y197 511-596 None
A0A6A2YXH2 605-687 None
A0A2N9IC49 429-509 None
A0A835RKQ7 36-141 None
A0A0B2P5G1 527-631 None
A0A4S8IQ18 902-1004 None
A2ZSM4 4-110 None
A0A314YGW1 139-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.