DPCstruct | MC14894

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)83 ± 8 aa
Standard deviation of domain lengths8.18
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score88.39
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)26.06
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U2RC70 18-87 QKKEFYQNGYGISIIPDVNNLELFEVAVLKGDKDNCVLCFDTHITDDVIKGLTADEVEMIKIEIKGLRKG
A0A7D5P3L4 5-84 RIHKIYRFPNDYGASVVNNPEGLHLFSGAFRMYVLRYTSPPPENCWEIADDTPITDGTLELKDWGEVESVLKRIMALPRP
A0A6N2Z2R8 7-92 None
A0A2D6XM01 4-87 None
A0A4S4CCQ7 8-112 None
A0A419IRE7 19-99 None
A0A6P2GTS0 7-89 None
A0A843GGE3 34-118 None
A0A6N3C0J8 6-81 None
A0A1M6P2W0 11-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.