DPCstruct | MC14887

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)84 ± 5 aa
Standard deviation of domain lengths4.57
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score87.98
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)33.43
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X3JX60 1-81 MHEYVVSTGDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRETRTYDRTAANGFKMT
A0A655YR16 1-79 MRQGDTLSQVFRNNELPLTDINALVKVEGSDKPLSQIQAGQLIRFKLAENGQLDILQLERNNQSVMFFRLSDGGFGRSK
A0A377D5M5 4-89 None
A0A2U3BA35 130-207 None
A0A418Y9I5 100-182 None
A0A7H4NGP1 1-86 None
A0A833IU76 118-198 None
A0A455W7L4 76-167 None
A0A090QQ75 61-150 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.